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Types of Medications Used in MAT

The medications used in MAT vary depending on the substance being treated. For opioid addiction, options include methadone, buprenorphine, and naltrexone. Methadone is a full opioid agonist that reduces withdrawal symptoms and cravings, while buprenorphine is a partial agonist that offers similar benefits with a lower risk of misuse³. Naltrexone, an opioid antagonist, works by blocking the effects of opioids altogether. For alcohol use disorder, naltrexone, acamprosate, and disulfiram are commonly prescribed, each targeting different aspects of addiction.